RESUMO
José Luis Arteta, fue uno de los últimos discípulos de Cajal. Él encarna como pocos la transición entre la brillante escuela neurohistológica española, con el inicio de la anatomía patológica diagnóstica de ámbito hospitalario asistencial. Esa transición ocurre durante la difícil posguerra en la década de los cuarenta e inicio de los cincuenta del siglo XX, hasta culminar con la fundación de la Sociedad Española de Anatomía Patológica en 1959. Como muchos de los patólogos de su generación, dominaba la práctica de las autopsias clínicas, pero en el Hospital Provincial de Madrid tuvo ocasión de desarrollar el diagnóstico biópsico de la mano del clínico más brillante de su generación Carlos Jiménez Díaz, al tiempo que mantenía una notable actividad investigadora en el Instituto Cajal y a través de su estrecha colaboración con Gregorio Marañón. Además de médico y patólogo, Arteta era un humanista, de vasta cultura, que también pudo desarrollar por su entrañable amistad con Pío Baroja. Sobre su prematura muerte a los 45 años por poliomielitis, queda una sombra de misterio acerca de si se trató de una infección ambiental o una inoculación accidental durante sus investigaciones sobre este virus.(AU)
José Luis Arteta, was one of Cajal's last students at the outstanding institute of neurohistology. His career highlights a time of transition in Spanish pathology during the difficult years between the 1940s and the early 1950s, following the Spanish civil war. Diagnostic pathology was beginning to take place within the hospital setting and eventually, in 1959, the Spanish Society of Pathology (SEAP) was founded. Like many of his peers, he was expert in clinical autopsies, but he also had the opportunity, in the Provincial Hospital in Madrid, to develop skills in biopsy diagnosis under the tutelage of Carlos Jimenez Díaz, the most brilliant clinician of the time. He continued his research at the Cajal Institute and in collaboration with Gregorio Marañón. However, not only was Arteta a notable physician and pathologist, he was also a cultured humanist and close friend of Pío Baroja. His premature death at age 45 from poliomyelitis remains somewhat of a mystery: was it caused by an environmental infection or an accidental inoculation during his research on the virus?.(AU)
Assuntos
Humanos , Masculino , História da Medicina , Patologia/história , Poliomielite , EspanhaRESUMO
Introducción. Las recomendaciones del cribado de cáncer de cérvix en España incluyen la participación en programas de control de calidad externos a los laboratorios de citología. La Sociedad Española de Citología ha iniciado un programa de control de calidad de la citología ginecológica. Objetivo. Presentar y discutir los resultados de la primera ronda del control de calidad de la Sociedad Española de Citología. Material y método. Organización de los hospitales participantes según el tipo de citología. Intercambio de preparaciones de 50 casos entre los participantes: 10 negativos, 20 ASCUS-ASCH, 10 LSIL y 10 HSIL. Estudio de la correlación diagnóstica interobservador. Resultados. Trece hospitales participantes: 6 en ThinPrep, 5 en triple toma y 2 en SurePath. La concordancia global media fue del 69,7%. La concordancia media por tipo de lesión fue del 41,7%. La concordancia en negativos fue del 78,1%, en ASCUS del 41,3%, en LSIL de 58,9% y en HSIL del 64,2%. Los casos discordantes se diagnosticaban con mayor frecuencia como negativos, ASCUS y LSIL. Las discordancias severas (HSIL/ASCH versus negativo), alcanzaron un 3,8% de casos. Conclusiones. Nuestros resultados son similares a los descritos en la literatura con muy escasas discordancias severas. El método de intercambio de laminillas utilizado no permite una formación continuada posterior, ya que no incluye la revisión de los casos con discordancias diagnósticas. Por ello, se contemplan correcciones metodológicas en sucesivas rondas (AU)
Introduction. The Spanish guidelines for cervical cancer screening recommend participating in external quality control programs. The Spanish Society of Cytology has started its own program of quality control for gynecological cytology. Aim. To describe and discuss the results of the first round of The Spanish Society of Cytology quality control for gynecological cytology. Material and method. Organization of participating hospitals on the basis of cytology type. Exchange of diagnostic slides from 50 cases among participants, as follows: 10 negative; 20 ASCUS-ASCH, 10 LSIL and 10 HSIL. Analysis of inter-observer correlation. Results. 13 hospitals took part: 6 with ThinPrep liquid-based cytology, 5 with conventional cytology, and 2 with SurePath liquid-based cytology. The global mean concordance was 69.7%. The mean concordance in the type of lesion was 41.7%. The concordance was 78.1% in negative diagnoses, 41.3%, in ASCUS, 58.9% in LSIL and 64.2% in HSIL The discordant cases were diagnosed more frequently as negative, ASCUS and LSIL. 3.8% of cases showed major discordances (HSIL or ASCH versus negatives). onclusions. Our results are similar to those reported in the literature, with very little severe discordance. The method of exchanging slides does not allows continuous training, since the review of discordant cases can not be made. Therefore, methodological corrections are contemplated for future rounds (AU)
Assuntos
Humanos , Feminino , Controle de Qualidade , Indicadores de Qualidade em Assistência à Saúde/organização & administração , Sociedades Médicas/normas , Neoplasias do Colo do Útero/diagnóstico , Colo do Útero/citologia , Neoplasias do Colo do Útero/patologia , Colo do Útero/patologia , Programas de Rastreamento/métodos , Erros de Diagnóstico/prevenção & controleRESUMO
No disponible
Assuntos
Humanos , Feminino , Teste de Papanicolaou/métodos , Teste de Papanicolaou/tendências , Técnicas Citológicas/história , Técnicas Citológicas/métodos , Técnicas Citológicas/tendências , Patologia/história , Patologia/métodos , Patologia Clínica/história , Patologia Clínica/métodosRESUMO
No disponible
Assuntos
Humanos , Feminino , Programas de Rastreamento/métodos , Neoplasias do Colo do Útero/patologia , Infecções por Papillomavirus/patologia , Neoplasias do Colo do Útero/prevenção & controle , Detecção Precoce de Câncer/métodos , Manejo de Espécimes/normas , Fatores EtáriosRESUMO
No disponible
Assuntos
Detecção Precoce de Câncer/métodos , Neoplasias do Colo do Útero/diagnóstico , Infecções por Papillomavirus/diagnóstico , Programas de Rastreamento/métodos , Testes Obrigatórios , Esfregaço Vaginal/métodos , Teste de Papanicolaou/métodos , Fatores Etários , Papillomaviridae/patogenicidade , Análise Custo-BenefícioRESUMO
No disponible
Assuntos
Humanos , Sociedades Médicas/história , Biologia Celular/tendências , Esfregaço Vaginal/históriaRESUMO
OBJECTIVE: To evaluate cytologic features of mammary myofibroblastoma in order to establish the possibility of precise preoperative recognition. STUDY DESIGN: This was a multi-institutional study of 6 patients with myofibroblastoma (5 men and 1 woman) in which preoperatively fine-needle aspiration cytology was performed. Four cases showed classical histologic features, 1 corresponded to the cellular variant and the remaining 1 to the fibrous form. RESULTS: Except for 1 case, smears were cellular and distributed as irregular aggregates and single cells. Most groups showed a small amount of metachromatic stroma and capillaries. Cells retained cytoplasm and showed a spindle-to-plump oval morphology with moderate pleomorphism. Nuclear pleomorphism was present and was relevant in 1 case. Intranuclear pseudoinclusions and mast cells were present in 3 cases. No epithelial clusters were seen. Due to hypercellularity and pleomorphism 1 case was considered as suspicious for malignancy. The remaining 5 were diagnosed as low-grade mesenchymal lesions, and myofibroblastoma was suggested in 3. CONCLUSION: Cytologic features of myofibroblastoma reflect what is seen on histology. When such findings are correlated with image studies, preoperative recognition can be possible. This is especially true for male patients in whom the tumor is relatively frequent.
